Initiation of DNA synthesis in cell cultures by colcemid.
نویسندگان
چکیده
Mitotic inhibitors (colcemid, colchicine, and vinblastine) initiate DNA synthesis in dense stationary cultures of mouse embryo fibroblast-like cells. This initiation is not due to any changes in local cell population density. Relationships between the activation of proliferation and other changes of interphase fibroblast-like cells produced by the mitotic inhibitors (disappearance of cytoplasmic microtubules and activation of movements of cell surface) are discussed.
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 68 5 شماره
صفحات -
تاریخ انتشار 1971